Senior Scientist I - Molecular Biology
Company Description
About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.
Job Description
Cell Line Development, PDS&T AbbVie isseekinga highly motivated and innovative Senior Scientist to join the Molecular Biology team within Cell Line Development in PDS&T. This role supports the development of AbbVies biologics pipeline by designing novel plasmids andoptimizinggenetic elements and vector architectures to enable robust recombinant protein expression and high-performing cell line development workflows. The successful candidate will bring strong molecular biologyexpertise, a deep understanding of gene regulation and expression control, and the ability to independently develop creative, scientifically rigorous solutions to complex technical challenges. This position offers the opportunity to shape platform capabilities through thoughtful construct engineering, experimental design, data-driven decision-making, and collaborative problem-solving in a fast-paced, cross-functional environment. Key Responsibilities - Lead the design and optimization of novel plasmid constructs for recombinant protein expression across multiple platforms.
- Optimizegenetic parts, regulatory elements, and vector architecture to improve expression performance, construct behavior, and platform compatibility.
- Apply strong molecular biologyexpertiseto support sequence analysis, construct design strategy, and experimental interpretation.
- Analyze complexsequence,construct, and experimental data to inform design decisions and next-step strategies.
- Contribute to platform optimization through innovation, process improvement, and scientific rigor.
- Support genetic characterization efforts, including activities relevant to regulatory filing and development documentation.
- Partner effectively with cross-functional teams across PDS&T and related functions to align scientific strategy with program and operational goals.
- Communicate findings, recommendations, and scientificrationale clearlyto internal stakeholders and leadership.
Qualifications
- BS with10+years, MS with8+years, orPhDwith0-2years
- Strongexpertisein molecular biology with extensive hands-on laboratory and design experience
- Demonstrated experience in vector design, expression construct optimization, and construct validation
- Strong understanding of gene regulation, sequence-element-driven expression control, and vector architecture
- Proven ability to independently design experiments, troubleshoot technical issues, and deliver high-quality scientific output
- Excellent communication, collaboration, and organizational skills
- Demonstrated scientific creativity, ownership, and ability to work with minimal supervision
Preferred - Experience supporting cell line development or related platform development activities
- Familiarity with late-stage genetic characterization and support for regulatory filing activities
- Experience with multipleintegrationsystems and platform-specific construct requirements
- Exposure to advanced sequence analysis tools, design software, or high-throughput molecular biology workflows
- Familiarity with bioinformatics, data-driven modeling, and model development
- Experience mentoring scientists or contributing to team development
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: - The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
- This job is eligible toparticipatein our short-term incentiveprograms.
Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssoleandabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html
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